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Rocilinostat
CAS No. 1316214-52-4
Rocilinostat ( ACY-1215 )
Catalog No. M11280 CAS No. 1316214-52-4
Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | In Stock |
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| 10MG | 55 | In Stock |
|
| 50MG | 71 | In Stock |
|
| 100MG | 104 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRocilinostat
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NoteResearch use only, not for human use.
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Brief DescriptionRocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay.
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DescriptionRocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay. It is >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2. Phase 2.
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SynonymsACY-1215
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC1; HDAC2; HDAC3; HDAC6; HDAC8
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1316214-52-4
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Formula Weight433.50
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Molecular FormulaC24H27N5O3
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Purity>98%(HPLC)
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SolubilityDMSO: 86 mg/mL (198.38 mM)
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SMILESO=C(C1=CN=C(N(C2=CC=CC=C2)C3=CC=CC=C3)N=C1)NCCCCCCC(NO)=O
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Chemical Name2-(diphenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Santo L, et al. Blood, 2012, 119(11), 2579-2589.
molnova catalog
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