Cart
sales@molnova.com
Rocilinostat
CAS No. 1316214-52-4
Rocilinostat ( ACY-1215 )
Catalog No. M11280 CAS No. 1316214-52-4
Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | In Stock |
|
| 10MG | 55 | In Stock |
|
| 50MG | 71 | In Stock |
|
| 100MG | 104 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameRocilinostat
-
NoteResearch use only, not for human use.
-
Brief DescriptionRocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay.
-
DescriptionRocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay. It is >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2. Phase 2.
-
SynonymsACY-1215
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorHDAC1; HDAC2; HDAC3; HDAC6; HDAC8
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1316214-52-4
-
Formula Weight433.50
-
Molecular FormulaC24H27N5O3
-
Purity>98%(HPLC)
-
SolubilityDMSO: 86 mg/mL (198.38 mM)
-
SMILESO=C(C1=CN=C(N(C2=CC=CC=C2)C3=CC=CC=C3)N=C1)NCCCCCCC(NO)=O
-
Chemical Name2-(diphenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Santo L, et al. Blood, 2012, 119(11), 2579-2589.
molnova catalog
related products
-
TH34
TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.
-
RGFP 966
RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM in cell-free assay, exhibits > 200-fold selectivity over other HDAC.
-
HDAC6-AR-IN-10
HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM.
